Vesugen dose range
The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 6 published studies are one click away.
Animal studies only Bioregulators Also called KED, Lys-Glu-Asp, vezugen, T-38
Common use ranges
From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. Oral amounts agree across two guides at 1 to 2 capsules or 10 to 20 mg a day. Injected amounts disagree by about 1000 times, from 10 mcg every other day to 10 mg a day. Sources are community and vendor guides only. No approved label exists in any country we found, and the published research comes almost entirely from one Russian research group.
Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.
- Half-life
- Not measured in any published study
- How it is taken
- Shot under the skin (subcutaneous), or oral capsule
- How long people use it
- 10 to 20 days in a row, then a break. The course is repeated every 3 to 6 months, which works out to 2 or 3 courses a year.
- Mixing used for the units
- 20 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 100 mcg.
Pick your vial size and how much water you add. The units below change to match.
20 mg vial + 2 mL water: 1 unit = 100 mcg
| Tier | Each dose | Syringe units20 mg vial + 2 mL water | How often | Schedule | Vial lastsat this tier |
|---|---|---|---|---|---|
| Starting [1] | 10 mcg | 0.1 units 0.00 mL | 3.5x a week | 10 mcg under the skin every other day for 10 to 20 days. | 6+ weeks |
| Typical [2] | 10 mg | 100 units 1.00 mL | once a day | 10 mg under the skin once a day for 10 to 20 days. | 2 days |
| Oral Typical [3] | 10 mg | Not a syringe dose | once a day | 10 mg (1 capsule in some packs) by mouth once a day for 10 to 30 days. | |
| Oral Higher [4] | 20 mg | Not a syringe dose | once a day | 20 mg (2 capsules in some packs) by mouth once a day for 10 to 20 days. | |
| Oral Maintenance [5] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day for a maintenance course. |
Good to know
- Oral strengths vary a lot by maker. Some packs list capsules, not milligrams, so the label on the box matters more than any range here.
- Some shops sell a product called Vesilute. It may or may not be the same peptide.
Sources for these amounts
- Starting: Peptide Assistant, Vesugen
- Typical: Peptide DB, Vesugen
- Oral Typical: Peptide Assistant, Vesugen · Peptide DB, Vesugen
- Oral Higher: Peptide Assistant, Vesugen · Peptide DB, Vesugen
- Oral Maintenance: Peptide DB, Vesugen
How long people use it: Peptide Assistant, Vesugen · Peptide DB, Vesugen · Khavinson bioregulator guide (IPS News)
Half-life: PubMed search, vesugen or Lys-Glu-Asp with pharmacokinetics or half-life, no relevant hits
Take the Vesugen chart with you
Get a one-page printable chart for Vesugen, with the syringe units for each vial and water mix. We can also email you when a new Vesugen study is published.
This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.
See the science: 6 published studies
No human dose data. No published human study of Vesugen states an amount given. Every figure on this page comes from animal studies.
Amounts given to animals in studies
Read this first. Only one living-animal study states a dose. Small Russian human studies gave it by mouth but no abstract states the amount. Lab dish work used 0.05 ng/ml and nanomolar levels.
Every study used for this page
Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.
| Study | Who was studied | Amount given, as reported | Route | How often | How long | What the authors reported |
|---|---|---|---|---|---|---|
| PMID 26390612Meshchaninov et al, Adv Gerontol 2015 | Human, 32 adults aged 41 to 83 with organic brain syndrome (vesugen and pinealon arms) | Not stated in the abstract | By mouth (stated by citing paper PMID 34071923, not in this abstract) | Not in abstract | Not in abstract | Improved biological age markers, more than pinealon. Lower CD34+ cells seen |
| PMID 23734521Bashkireva and Artamonova, Adv Gerontol 2012 | Human, 150 male truck drivers plus 150 metalworker controls | Not stated in the abstract | Not in abstract | Not in abstract | Not in abstract | Best psychoemotional result with vesugen plus pinealon combined |
| PMID 34071923Khavinson et al, Pharmaceuticals 2021 | Mouse, 5xFAD Alzheimer model, 10 per group | 400 mcg/kg | Into the belly (IP) | Once a day | 2 months (age 2 to 4 months) | KED tended to raise neuroplasticity and prevented dendritic spine loss |
| PMID 19110568Chalisova et al, Bull Exp Biol Med 2008 | Rat spleen explants, young and old | 0.05 ng/ml | Added to culture | Not in abstract | Not in abstract | Stimulated explant growth and blocked the growth-suppressing effect of cyclophosphamide 1 mg/ml |
| PMID 32399807Ashapkin et al, Mol Biol Rep 2020 | Human fetal bone marrow stem cell line | Not stated in the abstract | Added to culture | Not in abstract | Not in abstract | Raised IGF1 gene expression 3.5 to 5.6 fold, lowered FOXO1 |
| PMID 28539025Kozlov et al, Adv Gerontol 2016 | Human vessel lining cells, normal, atherosclerotic and restenotic | Not stated in the abstract | Added to culture | Not in abstract | Not in abstract | Normalised endothelin-1 and raised sirtuin-1 |
How to read the study numbers
- One study, one group. Each figure is what one team chose for its own participants or animals.
- Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
- Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
- Short studies. Many studies ran days or weeks. They do not show what happens over longer use.
Common questions
Is there a human dose for Vesugen?
No published human study of Vesugen states an amount given. The figures on this page come from animal studies only.
Where do these Vesugen numbers come from?
From 6 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.
How long does Vesugen stay in the body?
No published study has measured the half-life of Vesugen, so nobody knows exactly how long one dose stays in the blood.
Is this a recommendation for how much Vesugen to use?
No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.