Ovagen dose range
The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 5 published studies are one click away.
Animal studies only Bioregulators Also called EDL, Glu-Asp-Leu, T-35
Common use ranges
From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. Two community guides agree on 10 to 20 mg a day by mouth for 10 to 30 days, repeated every 3 to 6 months. Neither gives an injected amount. Sources are community and vendor guides only. No approved label exists in any country we found, and the published research comes almost entirely from one Russian research group.
Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.
- Half-life
- Not measured in any published study
- How it is taken
- Shot under the skin (subcutaneous), or oral capsule
- How long people use it
- 10 to 20 days in a row, then a break. The course is repeated every 3 to 6 months, which works out to 2 or 3 courses a year.
Includes amounts taken by mouth or in the nose. Those are not the same as a shot, see the route in each row below.
| Tier | Each dose | Syringe units | How often | Schedule | Vial lasts |
|---|---|---|---|---|---|
| Oral Typical [1] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day, the low end of the 10 to 20 mg range, for 10 to 30 days. | |
| Oral Higher [2] | 20 mg | Not a syringe dose | once a day | 20 mg by mouth once a day for 30 days. | |
| Oral Maintenance [3] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day for 10 to 15 days, every 4 to 6 months. |
Good to know
- Can be taken with or without food.
- Oral strengths vary a lot by maker. Some packs list capsules, not milligrams, so the label on the box matters more than any range here.
- No injected amount is given in the guides. Injectable vials are sold, but with no common dose attached.
Sources for these amounts
- Oral Typical: Peptide Assistant, Ovagen · Peptide DB, Ovagen
- Oral Higher: Peptide Assistant, Ovagen · Peptide DB, Ovagen
- Oral Maintenance: Peptide Assistant, Ovagen · Peptide DB, Ovagen
How long people use it: Peptide Assistant, Ovagen · Peptide DB, Ovagen · Khavinson bioregulator guide (IPS News)
Half-life: Khavinson et al 2022, transport of ultrashort peptides (no half-life data)
Take the Ovagen chart with you
Get a one-page printable chart for Ovagen, with the syringe units for each vial and water mix. We can also email you when a new Ovagen study is published.
This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.
See the science: 5 published studies
No human dose data. No published human study of Ovagen states an amount given. Every figure on this page comes from animal studies.
Amounts given to animals in studies
Read this first. Only one paper states an amount, read from its open full text. All kidney work is from one research group. A Khavinson patent (not peer reviewed) describes 34 hepatitis patients given 1 µg to 5 mg daily, with no PubMed record.
Every study used for this page
Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.
| Study | Who was studied | Amount given, as reported | Route | How often | How long | What the authors reported |
|---|---|---|---|---|---|---|
| PMID 28744634Zamorskii et al, Bull Exp Biol Med 2017 | Rat, random-bred, 150 to 200 g (n=42, 7 per group) | 3 mcg/kg (open full text) | Into the belly cavity (IP) | 40 min after each gentamicin dose (series I), or daily before ischemia (series II) | 6 days (gentamicin) or 3 days before ischemia | Prevented low urine output and urea buildup, less protein loss, protected antioxidant enzymes |
| PMID 26515176Zamorskii et al, Bull Exp Biol Med 2015 | Rat, cisplatin kidney failure (n NOT IN ABSTRACT) | Not stated in the abstract | NOT IN ABSTRACT | NOT IN ABSTRACT | NOT IN ABSTRACT | Strongest kidney protection of the peptides tested, normalized filtration and urine output |
| PMID 30607912Zamorskii et al, Adv Gerontol 2018 | Rat, old (n NOT IN ABSTRACT) | Not stated in the abstract | NOT IN ABSTRACT | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised urine output 1.2 to 1.4 times and sodium excretion 1.6 times, no kidney toxicity |
| PMID 25946838Khavinson et al, Adv Gerontol 2014 | Kidney cell cultures, young and aged | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised cell growth, lowered aging markers p16, p21, p53, raised SIRT-6 |
| PMID 24958378Khavinson et al, Bull Exp Biol Med 2014 | Primary kidney cell cultures, aging (peptide coded T-35) | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Main target was matrix enzyme MMP-14 |
How to read the study numbers
- One study, one group. Each figure is what one team chose for its own participants or animals.
- Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
- Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
- Short studies. Many studies ran days or weeks. They do not show what happens over longer use.
Common questions
Is there a human dose for Ovagen?
No published human study of Ovagen states an amount given. The figures on this page come from animal studies only.
Where do these Ovagen numbers come from?
From 5 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.
How long does Ovagen stay in the body?
No published study has measured the half-life of Ovagen, so nobody knows exactly how long one dose stays in the blood.
Is this a recommendation for how much Ovagen to use?
No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.