Cardiogen dose range
The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 5 published studies are one click away.
Animal studies only Bioregulators Also called AEDR, Ala-Glu-Asp-Arg
Common use ranges
From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. Injected amounts disagree. One guide gives 1 to 5 mg a day and another gives 10 mg a day, both for 10 to 20 days. Sources are community and vendor guides only. No approved label exists in any country we found, and the published research comes almost entirely from one Russian research group.
Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.
- Half-life
- Not measured in any published study
- How it is taken
- Shot under the skin (subcutaneous), or oral capsule
- How long people use it
- 10 to 20 days in a row, then a break. The course is repeated every 3 to 6 months, which works out to 2 or 3 courses a year.
- Mixing used for the units
- 25 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 125 mcg.
Pick your vial size and how much water you add. The units below change to match.
25 mg vial + 2 mL water: 1 unit = 125 mcg
| Tier | Each dose | Syringe units25 mg vial + 2 mL water | How often | Schedule | Vial lastsat this tier |
|---|---|---|---|---|---|
| Starting [1] | 1 mg | 8 units 0.08 mL | once a day | 1 mg under the skin once a day for 10 to 20 days, the low end of the 1 to 5 mg range. | about 4 weeks |
| Typical [2] | 5 mg | 40 units 0.40 mL | once a day | 5 mg under the skin once a day for 10 to 20 days, the top of the 1 to 5 mg range. | 5 days |
| Higher [3] | 10 mg | 80 units 0.80 mL | once a day | 10 mg under the skin once a day, in the belly or thigh, for 10 to 20 days. | 2 days |
| Oral Typical [4] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day, the low end of the 10 to 20 mg range, for 10 to 20 days. | |
| Oral Higher [5] | 20 mg | Not a syringe dose | once a day | 20 mg by mouth once a day, the top of the 10 to 20 mg range. | |
| Oral Maintenance [6] | 10 mg | Not a syringe dose | once a day | 10 mg by mouth once a day for a maintenance course. |
Good to know
- Injected courses run once a day, every day, for the length of the course. They are not taken all year.
- Oral strengths vary a lot by maker. Some packs list capsules, not milligrams, so the label on the box matters more than any range here.
- An unrelated Italian drug is also sold as Cardiogen. It is a carnitine syrup, not this peptide.
Sources for these amounts
- Starting: Peptide information page, Cardiogen
- Typical: Peptide information page, Cardiogen
- Higher: Peptide Assistant, Cardiogen
- Oral Typical: Peptide DB, Cardiogen
- Oral Higher: Peptide DB, Cardiogen
- Oral Maintenance: Peptide DB, Cardiogen
How long people use it: Peptide Assistant, Cardiogen · Peptide DB, Cardiogen · Peptide information page, Cardiogen · Khavinson bioregulator guide (IPS News)
Half-life: Khavinson et al 2022, transport of ultrashort peptides (no half-life data)
Take the Cardiogen chart with you
Get a one-page printable chart for Cardiogen, with the syringe units for each vial and water mix. We can also email you when a new Cardiogen study is published.
This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.
See the science: 5 published studies
No human dose data. No published human study of Cardiogen states an amount given. Every figure on this page comes from animal studies.
Read this first. No PubMed abstract gives an in-animal amount. Stated figures are cell or tissue culture only: 10(-12) M and 0.05 ng/ml in rat heart tissue. A Khavinson patent (not peer reviewed) lists 0.05 µg per rat after a heart attack.
Every study used for this page
Proof grade: Animal studies only. No human dose data has been published. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.
| Study | Who was studied | Amount given, as reported | Route | How often | How long | What the authors reported |
|---|---|---|---|---|---|---|
| PMID 20396706Levdik and Knyazkin, Bull Exp Biol Med 2009 | Rat, old, with transplanted M-1 sarcoma (n NOT IN ABSTRACT) | Not stated in the abstract | Injection, site NOT IN ABSTRACT | NOT IN ABSTRACT | NOT IN ABSTRACT | Slowed tumor growth through tumor vessel damage and more tumor cell death, not direct toxicity |
| PMID 20210190Chalisova et al, Adv Gerontol 2009 | Rat heart tissue explants, 3 and 24 months old | 10(-12) M | Added to tissue culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Strongly raised cell growth in young and old heart tissue, lowered p53 |
| PMID 17152728Zakutskii et al, Adv Gerontol 2006 | Rat heart tissue explants, young (3 weeks) and old (18 months) | 0.05 ng/ml | Added to tissue culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Stimulated growth of heart explants in young and old rats |
| PMID 22977870Khavinson et al, Bull Exp Biol Med 2012 | Mouse embryonic fibroblast cultures | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised cytoskeleton proteins 2 to 5 times and lamins A and C 2 to 3 times |
| PMID 20586252Kheifets et al, Adv Gerontol 2010 | Human prostate fibroblast cultures, young and aged passages | Not stated in the abstract | Added to cell culture | NOT IN ABSTRACT | NOT IN ABSTRACT | Raised CXCL12, WEDC1 and ghrelin in aged cultures |
How to read the study numbers
- One study, one group. Each figure is what one team chose for its own participants or animals.
- Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
- Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
- Short studies. Many studies ran days or weeks. They do not show what happens over longer use.
Common questions
Is there a human dose for Cardiogen?
No published human study of Cardiogen states an amount given. The figures on this page come from animal studies only.
Where do these Cardiogen numbers come from?
From 5 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Animal studies only.
How long does Cardiogen stay in the body?
No published study has measured the half-life of Cardiogen, so nobody knows exactly how long one dose stays in the blood.
Is this a recommendation for how much Cardiogen to use?
No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.