Peptide proof grades: how strong is the evidence?
Every peptide on this site gets one of three grades. The grade tells you how much research sits behind the numbers, before you read a single one.
Human trials
20 peptides
Tested in randomized human trials.
Small human studies
9 peptides
Only small or uncontrolled human studies.
Animal studies only
25 peptides
No human dose data has been published.
Human trials
At least one randomized trial gave the peptide to people, usually against a placebo, and published the amount. Some of these peptides are approved medicines with large trial programs. This is the strongest grade, but it still only covers the people, conditions and amounts those trials tested.
Small human studies
People were given the peptide, but in small groups, without a control group, or in short lab studies. The amounts are real, but a handful of people over a few days says little about safety or effect for anyone else.
Animal studies only
No published human study states an amount. Every study figure comes from rats, mice or other animals. Animal amounts are shown as the study gave them and are not human amounts. Any common use range for these peptides has never been tested in a study.
What a grade does not tell you
- It does not say a peptide works. A grade describes the type of evidence, not the result.
- It does not say a peptide is safe. Even the human trials ran for a limited time in specific groups.
- It does not cover products sold online. Studies used their own material under controlled conditions.