GHRP-6 dose range

The amounts people commonly use, from the low end to the high end, with syringe units, schedule and half-life. The 8 published studies are one click away.

Small human studies Growth hormone axis Also called Growth hormone releasing peptide 6, SK&F 110679

Common use ranges

From user guides and clinic write-ups. No drug label exists, and no study has tested these amounts in people. No drug label. Only one comparison guide gives amounts: 100 to 300 mcg a shot, 2 to 3 times a day.

Sources disagree, or there are very few. The amounts below come from a small number of guides, and they do not line up well. Treat every number on this page as uncertain, and check each source yourself.

Half-life
about 2.5 hours
How it is taken
subcutaneous injection
How long people use it
Not stated by the source.
Mixing used for the units
5 mg vial + 2 mL water. 1 unit on a U-100 insulin syringe = 25 mcg.
Total amount per day, by tier
Starting200 mcg / dayTypical300 mcg / dayHigher900 mcg / day
TierEach doseSyringe units5 mg vial + 2 mL waterHow oftenScheduleVial lastsat this tier
Starting [1]100 mcg4 units 0.04 mL2x a day100 mcg 2 times a dayabout 4 weeks
Typical [2]100 mcg4 units 0.04 mL3x a day100 mcg 3 times a day: morning, after a workout, before bed16 days
Higher [3]300 mcg12 units 0.12 mL3x a day200 to 300 mcg 2 to 3 times a day5 days

Good to know

  • GHRP-6 raises hunger more than GHRP-2. Some take it before meals for that reason.

Sources for these amounts

  1. Starting: Peptide-DB, GHRP-6 vs hexarelin
  2. Typical: Peptide-DB, GHRP-6 vs hexarelin
  3. Higher: Peptide-DB, GHRP-6 vs hexarelin

Half-life: Cabrales et al 2013, Eur J Pharm Sci, pharmacokinetic study in nine healthy men

This page shows what labels, clinics and users report, and what studies gave. It is not medical advice and not a recommendation for anyone. Many of these compounds are not approved for human use. Check your own medicines and lab work with a licensed clinician before using anything.

See the science: 8 published studies

Amounts given to people in studies

Lowest1 microgram per kilogram, one time, into a vein
Most used90 to 100 micrograms, one time, into a vein
Highest400 micrograms per kilogram, one time, into a vein

How it was given: into a vein

The 90 to 100 microgram amounts are flat, not per kilogram.

Amounts given to animals in studies

Lowest10 micrograms per kilogram, one time (rat)
Most used10 to 150 micrograms per kilogram, one time (rat)
Highest0.4 mg per kilogram daily for 7 days (rat)

Read this first. Nearly every human amount is a one-time pituitary test, not repeated use. The only repeated-use human figure, 100 micrograms three times a day, is from a 14-man chart review.

Every study used for this page

Proof grade: Small human studies. Only small or uncontrolled human studies. Amounts are quoted as each study reported them. Where the abstract does not state an amount, the row says so.

StudyWho was studiedAmount given, as reportedRouteHow oftenHow longWhat the authors reported
PMID 23099431Cabrales et al, Eur J Pharm Sci 2013Human, 9 healthy men100, 200 and 400 mcgrams/kgInto a vein, bolusOne time per dose levelSingle doses, blood taken 12 hoursClearing half of it took 2.5 hours, spread phase 7.6 minutes
PMID 8435889PeƱalva et al, Clin Endocrinol 1993Human, men plus 9 women1 mcgram/kgInto a veinOne time at minute 0Single doseGrowth hormone rose, not changed by sex or by alpha and beta blockers
PMID 7883854Popovic et al, J Clin Endocrinol Metab 1995Human, 12 patients with a cut pituitary stalk and 11 controls90 mcgramsInto a veinOne time per test3 separate test daysResponse was fully blocked when the stalk was cut, so it works mostly in the hypothalamus
PMID 15817913Haijma et al, Eur J Endocrinol 2005Human, 10 elderly men, 9 obese men, 7 controls93 mcgrams, with GHRH 100 mcgramsInto a vein, bolusOne timeSingle test, 2 hours of samplingResponse was much lower in severely obese men, so the usual cut-off does not fit them
PMID 28830317Sigalos et al, Am J Mens Health 2017Human, 14 men on testosterone (chart review)100 mcgrams, with GHRP-2 100 mcgrams and sermorelin 100 mcgramsNot in abstractThree times a dayAbout 134 days on averageIGF-1 went from about 160 to about 239 ng/mL
PMID 41901314Wang et al, Pharmaceuticals 2026Rat, heart attack model (coronary artery tied off)0.4 mg/kg, called the lowest amount that workedNot in abstractNot in abstract7 daysLess heart scarring and better pumping after the heart attack
PMID 15890336Depoortere et al, Eur J Pharmacol 2005Rat10 to 150 mcgrams/kgInto the bellyOne timeSingle doseSped up stomach emptying, like ghrelin and motilin
PMID 38873418Berlanga-Acosta et al, Front Pharmacol 2024Rat, doxorubicin-treatedNot stated in the abstractNot in abstractGiven alongside doxorubicinNot in abstractStopped the heart from stretching out and kept pumping normal

How to read the study numbers

  • One study, one group. Each figure is what one team chose for its own participants or animals.
  • Route matters. An amount given into a vein (IV) is not the same as the same amount under the skin, in the nose or by mouth.
  • Animals are not small people. An animal amount is shown as the study gave it. It is not a human amount.
  • Short studies. Many studies ran days or weeks. They do not show what happens over longer use.

Common questions

What amounts of GHRP-6 were used in human studies?

In the studies listed here, people were given from 1 microgram per kilogram, one time, into a vein up to 400 micrograms per kilogram, one time, into a vein. The amount used most often was 90 to 100 micrograms, one time, into a vein. These are what study teams chose for their participants under supervision.

Where do these GHRP-6 numbers come from?

From 8 published studies, each linked to its PubMed or ClinicalTrials.gov record. Every figure was checked against the study abstract or its open full text. Proof grade: Small human studies.

How long does GHRP-6 stay in the body?

Its half-life is about 2.5 hours in people. Half-life is how long it takes for half of a dose to leave the blood. The effect can last longer than that.

Is this a recommendation for how much GHRP-6 to use?

No. This page shows the amounts reported by drug labels, clinics and users, next to what researchers gave in studies. It is not medical advice and not a recommendation for anyone. Talk to a licensed clinician before using any of it.

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